Abnova

EIF4G3 Monoclonal Antibody (1H5)

EIF4G3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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EIF4G3 Antibody (H00008672-M03) in IHC (P)

Immunoperoxidase of monoclonal antibody to EIF4G3 on formalin-fixed paraffin-embedded human lung, adenosquamous cell carcinoma. Antibody concentration is 3 µg/mL.

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产品信息

H00008672-M03

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

免疫组化（石蜡） (IHC (P))

3 µg/mL

酶联免疫吸附实验 (ELISA)

1 ng/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b, kappa

分类

Monoclonal

类型

Antibody

克隆号

1H5

抗原

EIF4G3 (AAH30578, 1 a.a. approximately 515 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: MNSQPQTRSP FAAGPRPPHH QFFQRPQIQP PRATIPNSSP SIRPGAQTPT AVYQANQHIM MVNHLPMPYP VPQGPQYCIP QYRHSGPPYV GPPQQYPVQP PGPGPFYPGP GPGDFPNAYG TPFYPSQPVY QSAPIMVPTQ QQPPPAKREK KTIRIRDPNQ GGKDITEEII SGGGSRNPTP PIGRPTSTPT PPQQLPSQVP EHSPVVYGTV ESAHLAASTP VTAASDQKQE EKPKPDPVLK SPSPVLRLVL SGEKKEQEGQ TSETTAIVSI AELPLPPSPT TVSSVARSTI AAPTSSALSS QPIFTTAIDD RCELSSPRED TIPIPSLTSC TETSDPLPTN ENDGDICKKP CSVAPNDIPL VSSTNLINEI NGVSEKLSAT ESIVEIVKQE VLPLTLELEI LENPPEEMKL ECIPAPITPS TVPSFPPTPP TPPASPPHTP VIVPAAATTV SSPSAAITVQ RVLEEDESIR TCLSEDAKEI QNKIEVEADG QTEEILDSQN LNSRRSPVPE TSNEC

靶标信息

The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.

仅用于科研。不用于诊断过程。未经明确授权不得转售。