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ELF5 Monoclonal Antibody (3D10)

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ELF5 Antibody (H00002001-M01) in WB

Western Blot analysis of ELF5 expression in transfected 293T cell line by ELF5 monoclonal antibody (M01), clone 3D10.

Lane 1: ELF5 transfected lysate(30.1 KDa).
Lane 2: Non-transfected lysate.

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产品信息

H00002001-M01

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

酶联免疫吸附实验 (ELISA)

3 ng/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

3D10

抗原

ELF5 (NP_938195.1, 166 a.a. approximately 263 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: SRTSLQSSHL WEFVRDLLLS PEENCGILEW EDREQGIFRV VKSEALAKMW GQRKKNDRMT YEKLSRALRY YYKTGILERV DRRLVYKFGK NAHGWQED

靶标信息

ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: E74-like factor 5; E74-like factor 5 (ets domain transcription factor); elf-5; Epithelium-restricted ESE-1-related Ets factor; Epithelium-specific Ets transcription factor 2; ESE-2; ETS-related transcription factor Elf-5

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基因别名: ELF5; ESE2

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UniProt ID: (Human) Q9UKW6

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Entrez Gene ID: (Human) 2001

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功能

RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding winged helix/forkhead transcription factor

参与通路

ectodermal cell fate commitment regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter cell proliferation cell differentiation somatic stem cell population maintenance negative regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter mammary gland epithelial cell differentiation