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产品信息
PA5-28406
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 664 and 727 of Human ELMO1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545882
产品详细信息
Recommended positive controls: A431, H1299, HeLa, HepG2, N2a, PC-12, Neuro 2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. Similarity to a C. elegans protein suggests that this protein may function in apoptosis and in cell migration. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ced-12 homolog 1; engulfment and cell motility 1 splice 1; engulfment and cell motility 1, ced-12 homolog; Engulfment and cell motility protein 1; MGC126406; OTTHUMP00000207056; OTTHUMP00000207060; Protein ced-12 homolog
基因别名: 6330578D22Rik; C230095H21Rik; CED-12; CED12; ELMO-1; ELMO1; ELMO1s; KIAA0281
UniProt ID: (Human) Q92556, (Mouse) Q8BPU7
Entrez Gene ID: (Human) 9844, (Mouse) 140580, (Rat) 361251
phagocytosis, engulfment
apoptotic process
movement of cell or subcellular component
cell migration
Rac protein signal transduction
actin cytoskeleton organization
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of GTPase activity
vascular endothelial growth factor receptor signaling pathway
regulation of defense response to virus by virus
phagocytosis
actin filament-based process
