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产品信息
PA5-20913
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide near the amino terminus of human ELOVL7.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152322
产品详细信息
A suggested positive control is human liver tissue lysate.
PA5-20913 can be used with blocking peptide PEP-1027.
靶标信息
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-keto acyl-CoA synthase ELOVL7; Elongation of very long chain fatty acids protein 7; elongation of very long chain fatty acids-like 7; ELOVL FA elongase 7; ELOVL family member 7, elongation of long chain fatty acids; ELOVL fatty acid elongase 7; Very long chain 3-ketoacyl-CoA synthase 7; Very long chain 3-oxoacyl-CoA synthase 7; very-long-chain 3-oxoacyl-CoA synthase 7
基因别名: 9130013K24Rik; AI840082; ELOVL7
UniProt ID: (Human) A1L3X0, (Mouse) Q9D2Y9
Entrez Gene ID: (Human) 79993, (Mouse) 74559
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
fatty acid elongation, saturated fatty acid
fatty acid elongation, polyunsaturated fatty acid
very long-chain fatty acid biosynthetic process
unsaturated fatty acid biosynthetic process
sphingolipid biosynthetic process
fatty acid elongation, monounsaturated fatty acid
long-chain fatty-acyl-CoA biosynthetic process
