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ELP3 Antibody (MA5-27840) in ICC/IF
ELP3 Monoclonal Antibody (GT11811) detects ELP3 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ELP3 protein stained by ELP3 Monoclonal Antibody (GT11811) (Product # MA5-27840) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
Product Details
MA5-27840
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
GT11811
Immunogen
Recombinant protein encompassing a sequence within the center region of human ELP3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
2.35 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735174
Product Specific Information
Positive Control: HeLa, HeLa nuclear, 293T, A431, HeLa, HepG2
Predicted Reactivity: Mouse (96%), Zebrafish (92%), Drosophila (88%), Yeast (84%), Xenopus laevis (92%), Chicken (91%), Rhesus Monkey (100%), Bovine (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 2.3.1.48; elongation protein 3 homolog; Elongator complex protein 3; h KAT9; hELP3; tRNA uridine(34) acetyltransferase
Gene Aliases: ELP3; KAT9
UniProt ID: (Human) Q9H9T3
Entrez Gene ID: (Human) 55140
neuron migration
tRNA wobble uridine modification
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
central nervous system development
positive regulation of cell migration
histone H3 acetylation
histone H4 acetylation
regulation of protein kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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