Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 4
ENY2 Antibody (MA5-27843) in ICC/IF
ENY2 antibody detects ENY2 protein at Nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde/PBS for 15 min. Green: ENY2 protein stained by ENY2 antibody (Product # MA5-27843) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
MA5-27843
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
GT245
抗原
Recombinant protein encompassing a sequence within the center region of human ENY2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2735176
产品详细信息
Positive Control: U87-MG, SK-N-SH, IMR32
Predicted Reactivity: Mouse (100%), Zebrafish (85%), Xenopus laevis (93%), Pig (100%), Chicken (96%), Rhesus Monkey (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
ENY2 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: enhancer of yellow 2 homolog; Enhancer of yellow 2 transcription factor homolog; ENY 2; ENY-2; ENY2; Transcription and mRNA export factor ENY2
基因别名: DC6; e(y)2; ENY2; Sus1
UniProt ID: (Human) Q9NPA8
Entrez Gene ID: (Human) 56943, (Rat) 685258
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
protein transport
histone deubiquitination
poly(A)+ mRNA export from nucleus
positive regulation of transcription, DNA-templated
negative regulation of insulin secretion involved in cellular response to glucose stimulus
mRNA export from nucleus
