Invitrogen

EOMES Recombinant Rabbit Monoclonal Antibody (BLR104H)

查看其他35个EOMES抗体

产品信息

MA5-44399

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

-

免疫组化（石蜡） (IHC (P))

1:100-1:500

-

免疫细胞化学 (ICC/IF)

1:100-1:500

-

流式细胞分析 (Flow)

0.25 µL/1x10^6 cells

-

免疫沉淀 (IP)

6 µL/1 mg lysate

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

BLR104H

抗原

Peptide representing a region between residue 125 and 175 of Human eomesodermin homolog (EOMES).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

purified

保存液

BBS, pH 8.2

内含物

0.09% sodium azide

保存条件

4°C

运输条件

Wet ice

AB_2926529

产品详细信息

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

靶标信息

TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Eomesodermin homolog; T-box brain protein 2; T-brain-2

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基因别名: EOMES; TBR2

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UniProt ID: (Human) O95936

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Entrez Gene ID: (Human) 8320

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RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II activating transcription factor binding transcriptional repressor activity, RNA polymerase II transcription factor binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding Rel homology transcription factor

negative regulation of transcription from RNA polymerase II promoter endoderm formation mesoderm formation endodermal cell fate specification trophectodermal cell differentiation adaptive immune response CD8-positive, alpha-beta T cell differentiation involved in immune response transcription, DNA-templated brain development cardioblast differentiation stem cell population maintenance olfactory bulb development cerebral cortex regionalization cerebral cortex neuron differentiation interferon-gamma production skeletal muscle cell differentiation positive regulation of cell differentiation regulation of neuron differentiation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cell differentiation involved in embryonic placenta development mesodermal to mesenchymal transition involved in gastrulation