Fabgennix

EPAC1 Polyclonal Antibody, FITC

查看其他19个RAPGEF3抗体
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产品信息

EPAC-N-FITC

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:1,000
-

免疫组化 (IHC)

1:50-1:250
-

免疫细胞化学 (ICC/IF)

1:50-1:250
-

酶联免疫吸附实验 (ELISA)

1:10,000
-

免疫沉淀 (IP)

1:50-1:250
-

免疫电镜技术 (IM)

1:50-1:200
-
产品规格

种属反应

Horse, Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide taken within amino acid region 5-50 on Exchange Protein Directly Activated by cAMP protein.

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱 spectra

形式

Liquid

浓度

0.5-1.5 mg/mL

纯化类型

Affinity chromatography

保存液

proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Gene ontology (GO) annotation includes small GTPase mediated signal transduction. Target protein binds cAMP and activates the Ras superfamily guanine nucleotide binding protein (Rap1A)in a PKA-independent manner.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 9330170P05Rik; cAMP-GEFI; cAMP-regulated guanine nucleotide exchange factor I; cAMP-regulated guanine nucleotide exchange factor I (cAMP-GEFI); EPAC 1; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; MGC21410; Rap guanine nucleotide exchange factor (GEF) 3; Rap guanine nucleotide exchange factor 3; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

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基因别名: 2310016P22Rik; 9330170P05Rik; bcm910; CAMP-GEFI; CGEF1; EPAC; EPAC1; HSU79275; RAPGEF3

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UniProt ID: (Human) O95398, (Rat) Q9Z1C8, (Mouse) Q8VCC8

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Entrez Gene ID: (Horse) 100050541, (Human) 10411, (Rat) 59326, (Mouse) 223864

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功能
guanyl-nucleotide exchange factor activity protein binding Rap guanyl-nucleotide exchange factor activity protein domain specific binding cAMP binding ion channel binding cAMP-dependent protein kinase regulator activity nucleotide binding guanyl-nucleotide exchange factor
参与通路
angiogenesis signal transduction brain development cell proliferation negative regulation of cardiac muscle cell apoptotic process positive regulation of smooth muscle cell migration cAMP-mediated signaling spinal cord development positive regulation of cAMP catabolic process Rap protein signal transduction negative regulation of collagen biosynthetic process positive regulation of peptidyl-serine phosphorylation negative regulation of syncytium formation by plasma membrane fusion response to nicotine cellular response to drug positive regulation of GTPase activity positive regulation of angiogenesis positive regulation of cell size positive regulation of transcription from RNA polymerase II promoter positive regulation of protein export from nucleus regulation of insulin secretion positive regulation of stress fiber assembly positive regulation of syncytium formation by plasma membrane fusion artery development establishment of endothelial barrier cellular response to cAMP cellular response to transforming growth factor beta stimulus liver regeneration positive regulation of protein acetylation positive regulation of GTP binding positive regulation of calcium ion transmembrane transport positive regulation of hydrogen:potassium-exchanging ATPase activity cellular response to L-dopa dorsal root ganglion development regulation of actin cytoskeleton reorganization positive regulation of actin cytoskeleton reorganization regulation of histone H3-K9 acetylation regulation of protein kinase activity regulation of protein phosphorylation positive regulation of protein phosphorylation small GTPase mediated signal transduction positive regulation of ATPase activity intracellular signal transduction positive regulation of binding positive regulation of calcium ion transport negative regulation of cell death
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