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产品信息
PA5-120662
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human EPHX2 (NP_0019702)
偶联物
形式
Liquid
浓度
2.74 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914234
产品详细信息
Positive test controls include: 293T, LO2, SW480, Mouse liver, Mouse kidney, Mouse heart, Rat kidney. The target is usually found in the following locations: Cytoplasm, Peroxisome.
Immunogen sequence: LALPRGLLND AFQKGGPEGA TTRLMKGEIT LSQWIPLMEE NCRKCSETAK VCLPKNFSIK EIFDKAISAR KINRPMLQAA LMLRKKGFTT AILTNTWLDD RAERDGLAQL MCELKMHFDF LIESCQVGMV KPEPQIYKFL LDTLKASPSE VVFLDDIGAN LKPARDLGMV TILVQDTDTA LKELEKVTGI QLLNTPAPLP TSCNPSDMSH G
靶标信息
This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bifunctional epoxide hydrolase 2; CEH; cytosolic epoxide hydrolase; epoxide hydratase; epoxide hydrolase 2, cytoplasmic; epoxide hydrolase 2, cytosolic; epoxide hydrolase 2C; epoxide hydrolase, soluble; SEH; soluble epoxide hydrolase
基因别名: CEH; Eph2; EPHX2; SEH; sEP
UniProt ID: (Human) P34913, (Mouse) P34914, (Rat) P80299
Entrez Gene ID: (Human) 2053, (Mouse) 13850, (Rat) 65030
xenobiotic metabolic process
cellular calcium ion homeostasis
inflammatory response
regulation of blood pressure
response to toxic substance
positive regulation of gene expression
dephosphorylation
drug metabolic process
epoxygenase P450 pathway
cholesterol homeostasis
positive regulation of vasodilation
stilbene catabolic process
phospholipid dephosphorylation
reactive oxygen species metabolic process
regulation of cholesterol metabolic process
prostaglandin production involved in inflammatory response
lipid metabolic process
metabolic process
sensory perception of pain
aromatic compound catabolic process
linoleic acid metabolic process
positive regulation of blood pressure
