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Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (95%), Rat (94%), Zebrafish (81%), Pig (95%), Rhesus Monkey (100%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9; Endoplasmic reticulum lipid raft-associated protein 1; Erlin-1; OTTHUMP00000059425; OTTHUMP00000197867; Protein KE04; Protein KE04 homolog; SPFH domain family, member 1; SPFH domain-containing protein 1; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
基因别名: 2810439N09Rik; C10orf69; C80197; Erlin-1; ERLIN1; KE04; KEO4; RGD1307058; SPFH1; SPG62
UniProt ID: (Human) O75477, (Mouse) Q91X78
Entrez Gene ID: (Human) 10613, (Rat) 293939, (Mouse) 226144