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产品信息
MA5-34726
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JG34-42
抗原
Recombinant protein within Human ERp29 aa 1-142
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Wet ice
RRID
AB_2848634
产品详细信息
Positive Control: THP-1, F9, PMVEC, SiHa, rat testis tissue, human thyroid gland tissue, human colon cancer tissue.
靶标信息
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: endoplasmic reticulum lumenal protein ERp28; Endoplasmic reticulum resident protein 28; Endoplasmic reticulum resident protein 29; Endoplasmic reticulum resident protein 31; epididymis secretory protein Li 107; ERp28; ERp29; ERp31; protein disulfide isomerase family A, member 9
基因别名: C12orf8; ERP28; ERP29; ERp31; HEL-S-107; PDI-DB; PDIA9
UniProt ID: (Human) P30040
Entrez Gene ID: (Human) 10961
activation of MAPK activity
positive regulation of protein phosphorylation
protein folding
intracellular protein transport
protein secretion
positive regulation of gene expression
negative regulation of gene expression
protein unfolding
negative regulation of protein secretion
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
