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Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: endogenous retroviral sequence 3; Endogenous retrovirus group 3 member 1 Env polyprotein; endogenous retrovirus group 3, member 1; Envelope polyprotein; ERV-3 envelope protein; ERV-R envelope protein; ERV3 envelope protein; ERV3-1 envelope protein; HERV-R envelope protein; HERV-R_7q21.2 provirus ancestral Env polyprotein
Gene Aliases: envR; ERV-R; ERV3; ERV3-1; ERVR; HERV-R; HERVR
UniProt ID: (Human) Q14264
Entrez Gene ID: (Human) 2086
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