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A suggested positive control is rat colon lysate.
PA5-21109 can be used with blocking peptide PEP-1223.
RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Epithelial splicing regulatory protein 1; RNA binding motif protein 35A; RNA-binding motif protein 35A; RNA-binding protein 35A
基因别名: 2210008M09Rik; A630065D16; BC031468; ESRP1; RBM35A; RGD1560481; RMB35A
UniProt ID: (Human) Q6NXG1, (Mouse) Q3US41, (Rat) B2RYD2
Entrez Gene ID: (Human) 54845, (Mouse) 207920, (Rat) 500409