Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 5
ESRRG Antibody (PA5-27755) in WB
Western blot was performed using Anti-ESRRG Polyclonal Antibody (Product # PA5-27755) and a ~57 kDa band corresponding to Estrogen-related receptor gamma was observed across cell lines and tissues tested. Nuclear enriched extracts (30 µg lysate) of SH-SY5Y (Lane 1), SH-SY5Y treated with Retinoic Acid (Lane 2) and Mouse Brain (Lane 3) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0321BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (... View More
产品信息
PA5-27755
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment contain a sequence corresponding to a region within amino acids 53 and 435 of ERR gamma
偶联物
形式
Liquid
浓度
0.51 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545231
产品详细信息
Recommended positive controls: A431, mouse brain, rat spleen.
Predicted reactivity: Mouse (100%), Rat (100%), Chicken (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Estrogen-related receptor gamma (ERRG, ERR3, NR3B3) is an orphan member of the nuclear hormone receptor superfamily. ERRG acts as a transcription activator in the absence of a bound ligand. It binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. ERRG also induces the expression of PERM1 in the skeletal muscle.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DKFZp781L1617; ERR gamma; ERR gamma-2; Estrogen receptor-related protein 3; estrogen-related receptor 3; Estrogen-related receptor gamma; FLJ16023; Nuclear receptor subfamily 3 group B member 3
基因别名: ERR3; Errg; ERRG2; ERRgamma; ESRRG; KIAA0832; mKIAA0832; NR3B3
UniProt ID: (Human) P62508, (Mouse) O75454, (Rat) P62510
Entrez Gene ID: (Human) 2104, (Mouse) 26381, (Rat) 360896
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
steroid hormone receptor activity
retinoic acid receptor activity
steroid binding
protein binding
zinc ion binding
AF-2 domain binding
DNA binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
calmodulin binding
sequence-specific DNA binding
metal ion binding
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
intracellular receptor signaling pathway
steroid hormone mediated signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
transcription initiation from RNA polymerase II promoter
