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Recommended positive controls: 293T, A431, HeLa, HepG2, C8D30, PC-12.
Predicted reactivity: Mouse (96%), Rat (95%), Zebrafish (84%), Xenopus laevis (85%), Cat (96%), Pig (96%), Chicken (87%), Rhesus Monkey (98%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha-ETF; electron transfer flavoprotein alpha-subunit; Electron transfer flavoprotein subunit alpha, mitochondrial; electron transfer flavoprotein, alpha polypeptide; electron transferring flavoprotein, alpha polypeptide; electron-transfer-flavoprotein alpha polypeptide; glutaric aciduria II
基因别名: 2010200I21Rik; D9Ertd394e; EMA; ETF; ETFA; GA2; MADD
UniProt ID: (Human) P13804, (Mouse) Q99LC5, (Rat) P13803
Entrez Gene ID: (Human) 2108, (Mouse) 110842, (Rat) 300726