Invitrogen

ETV1 Polyclonal Antibody

ETV1 Antibody in Immunohistochemistry (IHC)

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ETV1 Antibody (PA5-41484) in IHC

Immunohistochemistry analysis of brain, cortex tissue using an anti-ETV1 polyclonal antibody (Product # PA5-41484).

ETV1 Antibody in Western Blot, Immunohistochemistry (WB, IHC)

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产品信息

PA5-41484

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

查看4篇已发表文章 4篇已发表文章

免疫组化 (IHC)

5 µg/mL

查看2篇已发表文章 2篇已发表文章

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human ETV1

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2608631

产品详细信息

Peptide sequence: PDNQRPLLKT DMERHINEED TVPLSHFDES MAYMPEGGCC NPHPYNEGYV

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 86%

靶标信息

ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The Etv1/Er81 transcription factor coordinates myelination-related genes to regulate Schwann cell differentiation and myelination.

Annals of translational medicine

Askar P,Xu J,Hu J,Shangguan J,Sun H,Zhou S,Yang X,Chen G,Su W,Gu Y

Published figure using ETV1 polyclonal antibody (Product # PA5-41484) in Western Blot

Mon Aug 01 00:00:00 UTC 2022

The Etv1/Er81 transcription factor coordinates myelination-related genes to regulate Schwann cell differentiation and myelination.

Annals of translational medicine

Askar P,Xu J,Hu J,Shangguan J,Sun H,Zhou S,Yang X,Chen G,Su W,Gu Y

Published figure using ETV1 polyclonal antibody (Product # PA5-41484) in Western Blot

Mon Aug 01 00:00:00 UTC 2022

Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer.

eLife

Inoue Y,Nikolic A,Farnsworth D,Shi R,Johnson FD,Liu A,Ladanyi M,Somwar R,Gallo M,Lockwood WW

Published figure using ETV1 polyclonal antibody (Product # PA5-41484) in Western Blot

Mon Jun 14 00:00:00 UTC 2021

Cross-testing of major molecular markers indicates distinct pathways of tumorigenesis in gastric adenocarcinomas and synchronous gastrointestinal stromal tumors.

Scientific reports

Kocsmár É,Kocsmár I,Szalai L,Lendvai G,Szijártó A,Schaff Z,Kiss A,Kovalszky I,Papp G,Lotz G

PA5-41484 was used in Immunohistochemistry to characterize nine MGs and GACs present in the same surgical specimen by cross-testing the markers of the major pathogenetic pathways of both tumor types.

Thu Dec 17 00:00:00 UTC 2020

Cross-testing of major molecular markers indicates distinct pathways of tumorigenesis in gastric adenocarcinomas and synchronous gastrointestinal stromal tumors.

Scientific reports

Kocsmár É,Kocsmár I,Szalai L,Lendvai G,Szijártó A,Schaff Z,Kiss A,Kovalszky I,Papp G,Lotz G

PA5-41484 was used in Immunohistochemistry to characterize nine MGs and GACs present in the same surgical specimen by cross-testing the markers of the major pathogenetic pathways of both tumor types.

Thu Dec 17 00:00:00 UTC 2020

The role of miR-24 as a race related genetic factor in prostate cancer.

Oncotarget

Hashimoto Y,Shiina M,Kato T,Yamamura S,Tanaka Y,Majid S,Saini S,Shahryari V,Kulkarni P,Dasgupta P,Mitsui Y,Sumida M,Deng G,Tabatabai L,Kumar D,Dahiya R

PA541484 was used in western blot to suggest that miR-24 is a central regulator of race-related prostate cancer

Tue Mar 07 00:00:00 UTC 2017

Differential expression of miR-34b and androgen receptor pathway regulate prostate cancer aggressiveness between African-Americans and Caucasians.

Oncotarget

Shiina M,Hashimoto Y,Kato T,Yamamura S,Tanaka Y,Majid S,Saini S,Varahram S,Kulkarni P,Dasgupta P,Mitsui Y,Sumida M,Tabatabai L,Deng G,Kumar D,Dahiya R

PA541484 was used in western blot to demonstrate that differential expression of miR-34b and AR are associated with prostate cancer aggressiveness in African-Americans