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产品信息
PA5-24226
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human ETV5
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2541726
靶标信息
ETS variant 5, transcription factor of the ETS family, divergent member of the winged helix-turn-helix superfamily, expressed in brain, placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ETS translocation variant 5; ets-related molecule; Ets-related protein ERM
基因别名: ERM; ETV5
UniProt ID: (Human) P41161
Entrez Gene ID: (Human) 2119
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription regulatory region DNA binding
transcription from RNA polymerase II promoter
neuromuscular synaptic transmission
locomotory behavior
cell differentiation
cellular response to oxidative stress
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
male germ-line stem cell asymmetric division
regulation of synapse organization
positive regulation of glial cell proliferation
regulation of branching involved in mammary gland duct morphogenesis
skeletal muscle acetylcholine-gated channel clustering
