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Sequence of this protein is as follows: LPEPGPQQQT FAVPRPPHQP LQMPKMMPEN QYPSEQRFQR QLSEPCHPFP PQPGVPGDNR PSYHRQMSEP IVPAAPPPPQ GFKQEYHDPL YEHGVPGMPG PPAHGFQSPM
ETS variant 5, transcription factor of the ETS family, divergent member of the winged helix-turn-helix superfamily, expressed in brain, placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ETS translocation variant 5; ets variant gene 5; ets variant gene 5 (ets-related molecule); ets-related molecule; Ets-related protein ERM
基因别名: 1110005E01Rik; 8430401F14Rik; ERM; ETV5
UniProt ID: (Human) P41161, (Mouse) Q9CXC9
Entrez Gene ID: (Human) 2119, (Rat) 303828, (Mouse) 104156