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EXOC2 Antibody (PA5-99983) in ICC/IF
Immunofluorescent analysis of EXOC2 in HepG2. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with EXOC2 polyclonal antibody (Product # PA5-99983) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Product Details
PA5-99983
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human EXOC2(Accession Q96KP1), corresponding to amino acid residues E53-Q103.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818916
Product Specific Information
Antibody detects endogenous levels of total SEC5/EXOC2.
Target Information
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Exocyst complex component 2; Exocyst complex component Sec5; rSec5; SEC5 homolog; SEC5-like 1
Gene Aliases: 2410030I24Rik; AI648199; EXOC2; Rsec5; SEC5; SEC5L1; Sec5p
UniProt ID: (Human) Q96KP1, (Mouse) Q9D4H1, (Rat) O54921
Entrez Gene ID: (Human) 55770, (Mouse) 66482, (Rat) 171455
Performance Guarantee
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