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Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous with the corresponding sequence in mouse and rat.
Specificity of this antibody: SEC10.
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 71 kDa component of rsec6/8 secretory complex; DKFZp666H126; Exocyst complex component 5; Exocyst complex component Sec10; hSec10; p71; p71 component of rsec6/8 secretory complex; SEC10-like 1
Gene Aliases: AI447711; AI448003; EXOC5; Gm76; HSEC10; PRO1912; SEC10; SEC10L1; SEC10P
UniProt ID: (Human) O00471, (Rat) P97878, (Mouse) Q3TPX4
Entrez Gene ID: (Human) 10640, (Rat) 60627, (Mouse) 105504
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