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EXOSC8 Antibody (PA5-98769) in WB
Western Blot analysis of EXOSC8 using a EXOSC8 Polyclonal antibody (Product # PA5-98769) at a concentration of 4 µg/mL. Lane 1: Mouse small intestine tissue. Lane 2: Hela whole cell lysate. Lane 3: K562 whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:10,000 dilution. Observed band size: 31 kDa.
产品信息
PA5-98769
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Exosome complex component RRP43 protein (2-276AA)
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2813382
靶标信息
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CBP-interacting protein 3; Exosome complex component RRP43; exosome complex exonuclease RRP43; Exosome component 8; OIP-2; Opa interacting protein 2; Opa-interacting protein 2; p9; Ribosomal RNA-processing protein 43; RP11-421P11.3
基因别名: 2310032N20Rik; bA421P11.3; CIP3; EAP2; EXOSC8; mKIAA4013; OIP2; p9; PCH1C; RRP43; Rrp43p
UniProt ID: (Human) Q96B26, (Mouse) Q9D753
Entrez Gene ID: (Human) 11340, (Mouse) 69639
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
biological_process
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
U1 snRNA 3'-end processing
U4 snRNA 3'-end processing
U5 snRNA 3'-end processing
regulation of mRNA stability
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
nuclear mRNA surveillance
nuclear polyadenylation-dependent rRNA catabolic process
nuclear polyadenylation-dependent tRNA catabolic process
nuclear polyadenylation-dependent mRNA catabolic process
