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Product Details
PA5-40545
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human EYA1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2605867
Product Specific Information
Peptide sequence: QDYPSYPSFG QGQYAQYYNS SPYPAHYMTS SNTSPTTPST NATYQLQEPP
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Target Information
This gene encodes a member of the eyes absent family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Eyes absent; Eyes absent homolog 1; MGC141875; OTTHUMP00000195053
Gene Aliases: BOP; BOR; BOS1; EYA1; OFC1
UniProt ID: (Human) Q99502
Entrez Gene ID: (Human) 2138
establishment of mitotic spindle orientation
metanephros development
branching involved in ureteric bud morphogenesis
outflow tract morphogenesis
double-strand break repair
transcription, DNA-templated
pattern specification process
mesodermal cell fate specification
sensory perception of sound
anatomical structure morphogenesis
response to ionizing radiation
striated muscle tissue development
histone dephosphorylation
protein sumoylation
cellular protein localization
establishment or maintenance of apical/basal cell polarity
peptidyl-tyrosine dephosphorylation
aorta morphogenesis
outer ear morphogenesis
middle ear morphogenesis
regulation of neuron differentiation
positive regulation of DNA repair
positive regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
neuron fate specification
embryonic skeletal system morphogenesis
semicircular canal morphogenesis
positive regulation of epithelial cell proliferation
pharyngeal system development
lung epithelial cell differentiation
otic vesicle morphogenesis
positive regulation of secondary heart field cardioblast proliferation
cochlea morphogenesis
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
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