Invitrogen

EYA1 Polyclonal Antibody

查看其他6个EYA1抗体

抗体检测数据 (2)

EYA1 Antibody in Immunohistochemistry (IHC)

EYA1 Antibody in Immunohistochemistry (IHC)

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EYA1 Antibody (PA5-40545) in IHC

Immunohistochemistry analysis of human kidney tissue using an anti-EYA1 polyclonal antibody (Product # PA5-40545).

EYA1 Antibody in Immunohistochemistry (IHC)

EYA1 Antibody in Western Blot (WB)

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EYA1 Antibody in Immunohistochemistry (IHC) — Immunohistochemistry analysis of human kidney tissue using an anti-EYA1 polyclonal antibody (Product # PA5-40545).

EYA1 Antibody in Western Blot (WB) — Western blot analysis of human brain cells using an anti-EYA1 polyclonal antibody (Product # PA5-40545).

产品信息

PA5-40545

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.2-1 µg/mL

-

免疫组化 (IHC)

5 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human EYA1

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2605867

产品详细信息

Peptide sequence: QDYPSYPSFG QGQYAQYYNS SPYPAHYMTS SNTSPTTPST NATYQLQEPP

Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

靶标信息

This gene encodes a member of the eyes absent family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Eyes absent; Eyes absent homolog 1; MGC141875; OTTHUMP00000195053

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基因别名: BOP; BOR; BOS1; EYA1; OFC1

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UniProt ID: (Human) Q99502

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Entrez Gene ID: (Human) 2138

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RNA binding protein tyrosine phosphatase activity protein binding metal ion binding

establishment of mitotic spindle orientation metanephros development branching involved in ureteric bud morphogenesis outflow tract morphogenesis double-strand break repair transcription, DNA-templated pattern specification process mesodermal cell fate specification sensory perception of sound anatomical structure morphogenesis response to ionizing radiation striated muscle tissue development histone dephosphorylation protein sumoylation cellular protein localization establishment or maintenance of apical/basal cell polarity peptidyl-tyrosine dephosphorylation aorta morphogenesis outer ear morphogenesis middle ear morphogenesis regulation of neuron differentiation positive regulation of DNA repair positive regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter neuron fate specification embryonic skeletal system morphogenesis semicircular canal morphogenesis positive regulation of epithelial cell proliferation pharyngeal system development lung epithelial cell differentiation otic vesicle morphogenesis positive regulation of secondary heart field cardioblast proliferation cochlea morphogenesis negative regulation of extrinsic apoptotic signaling pathway in absence of ligand