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Endothelial cell-specific molecule 1 is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.
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蛋白别名: Endothelial cell-specific molecule 1; ESM-1; IGFBP-rp6
基因别名: endocan; ESM1
UniProt ID: (Human) Q9NQ30
Entrez Gene ID: (Human) 11082