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For IHC applications, frozen sections processed with dry acetone are recommended. Paraformaldehyde is not recommended as it destroys the epitope.
Rat anti Human endothelin antibody, clone 3G10 reacts with the C terminal of endothelins 1, 2 and 3.
The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Big endothelin 1; Big endothelin-1; Big ET; Big ET 1; Big ET1; BigET; Endothelin-1; Et; ET-1; PPET1; Preproendothelin-1
基因别名: ARCND3; EDN1; ET1; HDLCQ7; PPET1; QME
UniProt ID: (Human) P05305
Entrez Gene ID: (Human) 1906