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产品信息
PA1-30291
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 913-943 amino acids from the C-terminal region of human EphA1
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_1957959
产品详细信息
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EPH tyrosine kinase; EPH tyrosine kinase 1; Ephrin type-A receptor 1; erythropoietin-producing hepatoma amplified sequence; Erythropoietin-producing hepatoma receptor; hEpha1; MGC163163; oncogene EPH; soluble EPHA1 variant 1; soluble EPHA1 variant 2; Tyrosine-protein kinase receptor EPH
基因别名: EPH; EPHA1; EPHT; EPHT1
UniProt ID: (Human) P21709
Entrez Gene ID: (Human) 2041
angiogenesis
positive regulation of cell-matrix adhesion
negative regulation of protein kinase activity
cell surface receptor signaling pathway
positive regulation of cell proliferation
peptidyl-tyrosine phosphorylation
positive regulation of cell migration
negative regulation of cell migration
substrate adhesion-dependent cell spreading
somatic stem cell population maintenance
regulation of GTPase activity
positive regulation of angiogenesis
protein autophosphorylation
ephrin receptor signaling pathway
positive regulation of stress fiber assembly
activation of GTPase activity
