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Ephrin B2 Antibody (PA5-106933) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Ephrin B2 in human meningeal carcinomatosis(MC) tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Ephrin B2 polyclonal antibody (Product # PA5-106933) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-106933
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human EFNB2(Accession P52799), corresponding to amino acid residues Y304-V333.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854597
产品详细信息
Antibody detects endogenous levels of total Ephrin B2.
靶标信息
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ELF-2; EPH-related receptor tyrosine kinase ligand 5; Ephrin-B2; HTK ligand; HTK-L; LERK-5; ligand of eph-related kinase 5; MGC126226; MGC126227; MGC126228
基因别名: EFNB2; ELF-2; Elf2; Epl5; EPLG5; Htk-L; HTKL; LERK-5; LERK5; NLERK-1
UniProt ID: (Human) P52799, (Mouse) P52800
Entrez Gene ID: (Human) 1948, (Mouse) 13642, (Rat) 306636
lymph vessel development
cell migration involved in sprouting angiogenesis
cell adhesion
cell-cell signaling
axon guidance
anatomical structure morphogenesis
organ morphogenesis
negative regulation of keratinocyte proliferation
T cell costimulation
viral entry into host cell
ephrin receptor signaling pathway
regulation of chemotaxis
nephric duct morphogenesis
positive regulation of cardiac muscle cell differentiation
angiogenesis
multicellular organism development
nervous system development
cell migration
cell differentiation
blood vessel morphogenesis
