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FAF1 Antibody (PA5-121137) in IHC (P)
Immunohistochemistry analysis of FAF1 in paraffin-embedded human lung cancer. Samples were incubated with FAF1 Polyclonal antibody (Product # PA5-121137). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol. 40x lens.
产品信息
PA5-121137
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide of human FAF1
偶联物
形式
Liquid
浓度
0.93 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914709
产品详细信息
Positive test controls include: HeLa, HL-60, SW620, Mouse testis. The target is usually found in the following locations: Nucleus.
靶标信息
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; hFAF1; TNFRSF6-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A
基因别名: AA408698; CGI-03; Dffrx; FAF1; Fam; hFAF1; HFAF1s; UBXD12; UBXN3A
UniProt ID: (Human) Q9UNN5, (Mouse) P54731, (Rat) Q924K2
Entrez Gene ID: (Human) 11124, (Mouse) 14084, (Rat) 140657
apoptotic process
cytoplasmic sequestering of NF-kappaB
cell death
positive regulation of cell death
regulation of cell adhesion
positive regulation of protein complex assembly
regulation of protein catabolic process
positive regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of protein kinase activity
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
biological_process
