Invitrogen

FAH Polyclonal Antibody

FAH Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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FAH Antibody (PA5-42050) in IHC (P)

Immunohistochemistry analysis of FAH was performed on fah-/- (left) and wildtype (right) mouse liver paraffin sections. To expose target proteins, antigen retrieval was performed by microwaving tissues for 8-15 minutes in 10mM sodium citrate buffer (pH 6.0). Following antigen retrieval, endogenous peroxidases were blocked with 3% hydrogen peroxide-methanol for 15 min at room temperature. Tissue slides were ... View More

FAH Antibody in Immunohistochemistry (IHC)

Product Image Gallery

FAH Antibody — Antibody specificity was demonstrated by comparing wildtype and FAH deficient mouse liver. FAH signal is detected only in the wildtype mouse liver (right panel) in IHC using Anti - FAH polyclonal Antibody (Product # PA5-42050). {KD}

产品信息

PA5-42050

应用

建议稀释比

已发表文章

免疫印迹 (WB)

2.5 µg/mL

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:400

产品规格

种属反应

Human, Mouse

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the C-terminal of human FAH (aa 311-360).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2609349

产品详细信息

Peptide sequence: AATICKSNFK YMYWTMLQQL THHSVNGCNL RPGDLLASGT ISGPEPENFG

Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%

靶标信息

This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury.

Proceedings of the National Academy of Sciences of the United States of America

Bailey AL,Kang LI,de Assis Barros D'Elia Zanella LGF,Silveira CGT,Ho YL,Foquet L,Bial G,McCune BT,Duarte-Neto AN,Thomas A,Raué HP,Byrnes K,Kallas EG,Slifka MK,Diamond MS

PA5-42050 was used in Immunohistochemistry to expand our understanding of viral hemorrhagic disease and associated coagulopathy and suggest directions for clinical management of severe YF cases.

Tue Dec 22 00:00:00 UTC 2020

Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury.

Proceedings of the National Academy of Sciences of the United States of America

Bailey AL,Kang LI,de Assis Barros D'Elia Zanella LGF,Silveira CGT,Ho YL,Foquet L,Bial G,McCune BT,Duarte-Neto AN,Thomas A,Raué HP,Byrnes K,Kallas EG,Slifka MK,Diamond MS

PA5-42050 was used in Immunohistochemistry to expand our understanding of viral hemorrhagic disease and associated coagulopathy and suggest directions for clinical management of severe YF cases.