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产品信息
PA5-51689
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641435
产品详细信息
Immunogen sequence: FTLDEVPKGK LHLRLEWLTL MPNASNLDKV LTDIKADKDQ ANDGLSSALL ILYLDSARNL PSGKKISSNP NPVVQMSVGH KAQESKIRYK TNEPVWEENF TFFIHNPKRQ DLEVEVRDEQ HQ
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.
靶标信息
Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (PubMed:27044890). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: chr2 synaptotagmin; Chr2Syt; E-Syt2; extended synaptotagmin like protein 2; extended synaptotagmin protein 2; Extended synaptotagmin-2; extended synaptotagmin-like protein 2; family with sequence similarity 62 (C2 domain containing), member B
基因别名: CHR2SYT; E-Syt2; ESYT2; FAM62B; KIAA1228
UniProt ID: (Human) A0FGR8
Entrez Gene ID: (Human) 57488
