Invitrogen

FAM83D Polyclonal Antibody

FAM83D Antibody in Immunocytochemistry (ICC/IF)

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FAM83D Antibody (PA5-140100) in ICC/IF

Immunofluorecent analysis of FAM83D in human cell line A-431 using FAM83D Polyclonal Antibody (Product # PA5-140100). Staining shows localization to cytosol and mitotic spindle.

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产品信息

PA5-140100

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human FAM83D. Recombinant protein control fragment (Product #RP-108985).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2927102

产品详细信息

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Immunogen sequence: ASSTGSPASI RTTDFHNPGY PKYLGTPHLE LYLSDSLRNL NKERQFHFAG IRSRLNHMLA MLSRRTLFTE NHLGLHSGNF S

靶标信息

Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.

仅用于科研。不用于诊断过程。未经明确授权不得转售。