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产品信息
PA5-59187
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641483
产品详细信息
Immunogen sequence: RIMEEKALEV YDLIRTIRDP EKPNTLEELE VVSESCVEVQ EINEEEYLVI IRFTPTVPHC SL
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.
靶标信息
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytosolic iron-sulfur assembly component 2A; family with sequence similarity 96, member A; MIP18 family protein FAM96A
基因别名: CIA2A; CIAO2A; FAM96A
UniProt ID: (Human) Q9H5X1
Entrez Gene ID: (Human) 84191
