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FANCI Antibody (PA5-59014) in ICC/IF
Immunofluorescence analysis of KIAA1794 was performed using Jurkat cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with KIAA1794 Polyclonal Antibody (Product # PA5-59014) at 1:100 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at a dilution... View More
产品信息
PA5-59014
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2643072
产品详细信息
Immunogen sequence: YGKGVLSGEE CKKQLINTLC SGRWDQQYVI QLTSMFKDVP LTAEEVEFVV EKALSMFSKM NLQEIPPLVY QLLVLSSKGS RKSVLEGIIA FFSALDKQHN EEQSGDELLD VVTVPSGE
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 73%.
靶标信息
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Fanconi anemia group I protein; Fanconi anemia, complementation group I; Protein FACI
基因别名: FANCI; KIAA1794
UniProt ID: (Human) Q96ST0
Entrez Gene ID: (Human) 55215
