Abnova

FBLN1 Polyclonal Antibody, MaxPab™

图: 1 / 1

FBLN1 Antibody (H00002192-B01P) in WB

Western Blot analysis of FBLN1 expression in transfected 293T cell line by FBLN1 MaxPab polyclonal antibody. Lane 1: FBLN1 transfected lysate(75.13 KDa). Lane 2: Non-transfected lysate. .

Product Image Gallery

产品信息

H00002192-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

FBLN1 (AAH22497.1, 1 a.a. approximately 683 a.a) full-length human protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.3 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MERAAPSRRV PLQLLLLGGL ALLAAGVDAD VLLEACCADG HRMATHQKDC SLPYATESKE CRMVQEQCCH SQLEELHCAT GISLANEQDR CATPHGDNAS LEATFVKRCC HCCLLGRAAQ AQGQSCEYSL MVGYQCGQVF RACCVKSQET GDLDVGGLQE TDKIIEVEEE QEDPYLNDRC RGGGPCKQQC RDTGDEVVCS CFVGYQLLSD GVSCEDVNEC ITGSHSCRLG ESCINTVGSF RCQRDSSCGT GYELTEDNSC KDIDECESGI HNCLPDFICQ NTLGSFRCRP KLQCKSGFIQ DALGNCIDIN ECLSISAPCP IGHTCINTEG SYTCQKNVPN CGRGYHLNEE GTRCVDVDEC APPAEPCGKG HRCVNSPGSF RCECKTGYYF DGISRMCVDV NECQRYPGRL CGHKCENTLG SYLCSCSVGF RLSVDGRSCE DINECSSSPC SQECANVYGS YQCYCRRGYQ LSDVDGVTCE DIDECALPTG GHICSYRCIN IPGSFQCSCP SSGYRLAPNG SNCQDIDECV TGIHNCSINE TCFNIQGGFR CLAFECPENY RRSAATRCER LPCHENRECS KLPLRITYYH LSFPTNIQAP AVVFRMGPSS AVPGDSMQLA ITGGNEEGFF TTRKVSPHSG VVALTKPVPE PRDLLLTVKM DLSRHGTVSS FVAKLFIFVS AEL

靶标信息

Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes and blood. Fibulin-1 self associates as well as binds to calcium, fibronectin, laminin, nidogen and fibrinogen. These interactions, individually or in combination, may account for the observed association of Fibulin-1 with basement membranes, connective tissue, elastic fibers and fibrin clots. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. Other studies point to the inhibition of cancer cell motility with increasing exposure to Fibulin-1. The exact function of Fibulin-1 in the cell is unknown.

仅用于科研。不用于诊断过程。未经明确授权不得转售。