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产品信息
PA5-107126
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide located within the following region: IRAFQHAFST NDCSRNVYIK KNGFTLHRNP IAQSTDGART KIGFSEGRHA
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.4, with 2% sucrose
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2817842
产品详细信息
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
靶标信息
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons. May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F-box only protein 45; F-box/SPRY domain-containing protein 1; hFbxo45
基因别名: FBX45; FBXO45
UniProt ID: (Human) P0C2W1
Entrez Gene ID: (Human) 200933
neuron migration
cellular response to DNA damage stimulus
protein ubiquitination
cerebral cortex radially oriented cell migration
cerebral cortex tangential migration
corticospinal tract morphogenesis
anterior commissure morphogenesis
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
synapse assembly involved in innervation
