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Immunogen sequence: EGTGFYPSEP MLCSESVEGQ VPHSLETLYQ SADCSDANDA LIVLIHLLML ESGYIPQGTE AKALSMPEKW KLSGVYK
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 81%.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686B08113; F-box only protein 7
基因别名: FBX; FBX07; FBX7; FBXO7; PARK15; PKPS
UniProt ID: (Human) Q9Y3I1
Entrez Gene ID: (Human) 25793