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产品信息
PA5-116803
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 500-598 of human FBXW8 (NP_6991792)
偶联物
形式
Liquid
浓度
1.46 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901434
产品详细信息
Positive Samples: U-87MG, A-549, A-431, Rat lung, Rat heart
Immunogen sequence: WDYRMNQKLW EVYSGHPVQH ISFSSHSLIT ANVPYQTVMR NADLDSFTTH RRHRGLIRAY EFAVDQLAFQ SPLPVCRSSC DAMATHYYDL ALAFPYNHV
靶标信息
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F-box and WD-40 domain protein 8; F-box and WD-40 domain-containing protein 8; F-box only protein 29; F-box protein FBX29; F-box/WD repeat-containing protein 8; MGC33534
基因别名: 4930438M06Rik; FBW6; FBW8; FBX29; FBXO29; FBXW6; FBXW8
UniProt ID: (Human) Q8N3Y1, (Mouse) Q8BIA4
Entrez Gene ID: (Human) 26259, (Rat) 304522, (Mouse) 231672
