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产品信息
PA5-28832
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 22 and 86 of Human FCER1G
偶联物
形式
Liquid
浓度
0.73 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546308
产品详细信息
Recommended positive controls: Fc epsilonRIgamma tansfected 293T cell.
Predicted reactivity: Rat (100%), Dog (100%), Pig (100%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fc epsilon receptor Ig; Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide; Fc receptor gamma-chain; Fc-epsilon RI-gamma; FceRI gamma; FcRgamma; High affinity immunoglobulin epsilon receptor subunit gamma; IgE Fc receptor subunit gamma; immunoglobulin E receptor, high affinity, gamma chain
基因别名: AI573376; CD23; Fce1g; FcepsilonRI; FCER1G; FcR-gamma; FcR[g]; FCRG; FcRgamma; Ly-50
UniProt ID: (Human) P30273, (Mouse) P20491
Entrez Gene ID: (Human) 2207, (Mouse) 14127
positive regulation of type IIa hypersensitivity
positive regulation of type III hypersensitivity
positive regulation of type I hypersensitivity
stimulatory C-type lectin receptor signaling pathway
neutrophil activation involved in immune response
T cell differentiation involved in immune response
Fc receptor mediated stimulatory signaling pathway
serotonin secretion by platelet
phagocytosis, engulfment
integrin-mediated signaling pathway
blood coagulation
regulation of platelet activation
immunoglobulin mediated immune response
antigen processing and presentation of exogenous peptide antigen via MHC class II
platelet activation
neutrophil chemotaxis
receptor internalization
positive regulation of interleukin-10 production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of mast cell cytokine production
negative regulation of mast cell apoptotic process
Fc-gamma receptor signaling pathway
Fc-epsilon receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I
defense response to bacterium
positive regulation of mast cell degranulation
innate immune response
mast cell activation
positive regulation of phagocytosis
leukocyte migration
cellular response to low-density lipoprotein particle stimulus
protein localization to plasma membrane
signal transduction
cell surface receptor signaling pathway
regulation of immune response
positive regulation of immune response
