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Product Details
PA5-97111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 27-290 of human FcRn (NP_0040981)
Conjugate
Form
Liquid
Concentration
2.55 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808913
Product Specific Information
Immunogen sequence: HLSLLYHLTA VSSPAPGTPA FWVSGWLGPQ QYLSYNSLRG EAEPCGAWVW ENQVSWYWEK ETTDLRIKEK LFLEAFKALG GKGPYTLQGL LGCELGPDNT SVPTAKFALN GEEFMNFDLK QGTWGGDWPE ALAISQRWQQ QDKAANKELT FLLFSCPHRL REHLERGRGN LEWKEPPSMR LKARPSSPGF SVLTCSAFSF YPPELQLRFL RNGLAAGTGQ GDFGPNSDGS FHASSSLTVK SGDEHHYCCI VQHAGLAQPL RVEL
Positive Samples: HL-60, Mouse brain, Mouse small intestine, Mouse liver, Mouse kidney; Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
FCGRT binds to the Fc region of monomeric immunoglobulins gamma. It mediates the uptake of IgG from milk. It plays a possible role in transfer of immunoglobulin G from mother to fetus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fc fragment immunoglobulin G receptor; Fc fragment of IgG, receptor, transporter, alpha; Fc receptor, IgG, alpha chain transporter; FcRn; FcRn alpha chain; heavy chain of the major histocompatibility complex class I-like Fc receptor; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig; transmembrane alpha chain of the neonatal receptor
Gene Aliases: alpha-chain; FCGRT; FCRN
UniProt ID: (Human) P55899, (Rat) P13599, (Mouse) Q61559
Entrez Gene ID: (Human) 2217, (Rat) 29558, (Mouse) 14132
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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