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产品信息
PA5-28912
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 395 of Human Squalene synthetase(SQS)
偶联物
形式
Liquid
浓度
0.97 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546388
产品详细信息
Recommended positive controls: 293T, A431, H1299, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (88%), Rat (86%), Pig (91%), Chicken (80%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Farnesyl-diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase 1; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; Squalene synthase; squalene synthetase
基因别名: DGPT; ERG9; FDFT1; SQS; SS
UniProt ID: (Human) P37268
Entrez Gene ID: (Human) 2222
