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产品信息
MA5-25676
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Non-human primate
已发表种属
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI2F10
抗原
Full length human recombinant protein of FDFT1 produced in HEK293T cell
偶联物
形式
Liquid
浓度
0.93 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723174
靶标信息
FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Farnesyl-diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase 1; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; Squalene synthase; squalene synthetase
基因别名: DGPT; ERG9; FDFT1; SQS; SS
UniProt ID: (Human) P37268
Entrez Gene ID: (Human) 2222
