Invitrogen

FEN1 Polyclonal Antibody

FEN1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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FEN1 Antibody (PA5-82261) in IHC (P)

Immunohistochemical analysis of FEN1 in human kidney using FEN1 Polyclonal Antibody (Product # PA5-82261) shows low expression as expected.

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FEN1 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of FEN1 demonstrates antibody specificity. Immunohistochemical analysis of FEN1 using anti-FEN1 Polyclonal Antibody (Product #PA5-82261), shows significant staining of FEN1 in lymph node and shows minimal or weak staining in kidney tissues. The relative expression levels of FEN1 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-82261

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human FEN1. Recombinant protein control fragment (Product #RP-89493).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2789421

产品详细信息

Immunogen sequence: CAALVKAGKV YAAATEDMDC LTFGSPVLMR HLTASEAKKL PIQEFHLSRI LQELGLNQEQ FVDLCILLGS DYCESIRGIG PKRAVDLIQK HKSIEEIVRR LDPNKYPVPE NWLHKEAHQL FLEPEVLDPE SVELKW

靶标信息

FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DNase IV; FEN-1; FEN-1 {ECO:0000255|HAMAP-Rule:MF_03140}; FEN1; fen1 {ECO:0000255|HAMAP-Rule:MF_03140}; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255|HAMAP-Rule:MF_03140}; Flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255|HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1

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基因别名: AW538437; FEN-1; FEN1; MF1; RAD2

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UniProt ID: (Human) P39748, (Rat) Q5XIP6

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Entrez Gene ID: (Human) 2237, (Mouse) 14156, (Rat) 84490

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