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产品信息
PA5-51568
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641592
产品详细信息
Immunogen sequence: DSAQAKRKYQ EASKDKDRDK AKDKYVRSLW KLFAHHNRYV LGVRAAQLHH QHHHQLLLPG LLRSLQDLHE EMACILKEIL QEYLEISSLV QDEVVAIHRE MAAAAARIQP EAEYQGFLRQ YGSAPDVPPC VTFDESLLEE GEPLEP
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 90%.
靶标信息
FES (FPS) is a tyrosine protein kinase that is required for maintenance of cellular transformation. Its chromosomal location is linked to a specific translocation event identified in patients with acute promyelocytic leukemia, and it is also involved in normal hematopoiesis. Alternative splicing results in multiple variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 2.7.10.2; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog; feline sarcoma oncogene; Feline sarcoma/Fujinami avian sarcoma oncogene homolog; Oncogene FES, feline sarcoma virus; p93c-fes; Proto-oncogene c-Fes; Proto-oncogene c-Fps; proto-oncogene tyrosine-protein kinase Fes/Fps; Tyrosine-protein kinase Fes/Fps; Variant 4
基因别名: FES; FPS
UniProt ID: (Human) P07332
Entrez Gene ID: (Human) 2242
microtubule bundle formation
protein phosphorylation
chemotaxis
epidermal growth factor receptor signaling pathway
multicellular organism development
cell proliferation
regulation of cell shape
positive regulation of neuron projection development
peptidyl-tyrosine phosphorylation
regulation of cell adhesion
positive regulation of microtubule polymerization
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
regulation of mast cell degranulation
innate immune response
regulation of cell differentiation
positive regulation of myeloid cell differentiation
protein autophosphorylation
centrosome organization
regulation of vesicle-mediated transport
regulation of cell motility
positive regulation of actin cytoskeleton reorganization
