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FEZ1 Antibody (PA5-90412) in WB
Western blot analysis of FEZ1 in extracts of various cell lines. Samples were incubated with FEZ1 Polyclonal antibody (Product # PA5-90412) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 10s.
产品信息
PA5-90412
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human FEZ1 (NP_0050941)
偶联物
形式
Liquid
浓度
0.52 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806059
产品详细信息
Immunogen sequence: MEAPLVSLDE EFEDLRPSCS EDPEEKPQCF YGSSPHHLED PSLSELENFS SEIISFKSME DLVNEFDEKL NVCFRNYNAK TENLAPVKNQ LQIQEEEETL QDEEVWDALT DNYIPSLSED WRDPNIEALN GNCSDTEIHE KEEEEFNEKS ENDSGINEEP; Positive Samples: Mouse brain, Rat brain; Cellular Location: Cell membrane, Cytoplasm, centrosome, cytoskeleton, microtubule organizing center
靶标信息
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F37; Fasciculation and elongation protein zeta-1; protein kinase C-binding protein Zeta1; zygin 1; Zygin I; Zygin-1
基因别名: Fez1; UNC-76; UNC76
UniProt ID: (Rat) P97577, (Mouse) Q8K0X8
Entrez Gene ID: (Rat) 81730, (Mouse) 235180
