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FGD2 Antibody (PA5-48526) in IHC (P)
Immunohistochemistry analysis of FGD2 in formalin fixed and paraffin embedded human kidney tissue. Samples were incubated with FGD2 polyclonal antibody (Product # PA5-48526) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-48526
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 508-537 amino acids from the C-terminal region of human FGD2.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2633983
靶标信息
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5- bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4- monophosphate and phosphatidylinositol 3-monophosphate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: faciogenital dysplasia homolog 2; faciogenital dysplasia protein 2; FGD1 family, member 2; Fgd2-like protein; FLJ00276 protein; FYVE, RhoGEF and PH domain-containing protein 2; t-complex distorter 2; Zinc finger FYVE domain-containing protein 4
基因别名: FGD2; Tcd-2; Tcd2; tcs-2; tcs2; ZFYVE4
UniProt ID: (Human) Q7Z6J4, (Mouse) Q8BY35
Entrez Gene ID: (Human) 221472, (Mouse) 26382
cytoskeleton organization
regulation of cell shape
actin cytoskeleton organization
regulation of Rho protein signal transduction
positive regulation of apoptotic process
regulation of GTPase activity
positive regulation of JUN kinase activity
positive regulation of GTPase activity
filopodium assembly
regulation of small GTPase mediated signal transduction
