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产品信息
PA5-56074
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641598
产品详细信息
Immunogen sequence: VTVFENSRTP EAAPRGQRLE DVHHRPECRP PESPGPREKT NVGEAVGSEP RTVSRRYLNS LKNKLSSEAW RKSCQPVTLS GSGTQEPEKK IVQEL
Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 63%.
靶标信息
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5- bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4- monophosphate and phosphatidylinositol 3-monophosphate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FGD1 family, member 2; FLJ00276 protein; FYVE, RhoGEF and PH domain-containing protein 2; Zinc finger FYVE domain-containing protein 4
基因别名: FGD2; ZFYVE4
UniProt ID: (Human) Q7Z6J4
Entrez Gene ID: (Human) 221472
cytoskeleton organization
regulation of cell shape
actin cytoskeleton organization
regulation of Rho protein signal transduction
positive regulation of apoptotic process
regulation of GTPase activity
positive regulation of JUN kinase activity
positive regulation of GTPase activity
filopodium assembly
regulation of small GTPase mediated signal transduction
