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FGF-8A Antibody (MA5-50507) in IHC
Immunohistochemical analysis of FGF-8A using FGF-8A Recombinant Monoclonal Antibody (Product # MA5-50507) on 1 day-post-fertilization zebrafish embryo whole mount at a dilution of 1:200 (Green). Tris-HCl buffer, pH 9.0, 20 min at 70°C was used for Antigen retrieval.
产品信息
MA5-50507
产品规格
种属反应
Zebrafish
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL2369
抗原
Recombinant fragment of zebrafish Fgf8a.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3092947
靶标信息
FGF-8 is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8a, FGF-8b, FGF-8e and FGF-8f. The human and murine FGF-8a and FGF-8b are identical, unlike human and mouse FGF-8e and FGF-8f, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ace; acerebellar; cb110; etID309886.13; fb73a06; FGF-8; fgf8; Fibroblast growth factor 8; fibroblast growth factor 8 a; ibd5031; secreted protein
基因别名: ace; cb110; etID309886.13; fgf-8; fgf8; fgf8a; id:ibd5031; wu:fb73a06
UniProt ID: (Zebrafish) O57341
Entrez Gene ID: (Zebrafish) 30538
cell fate specification
somitogenesis
positive regulation of protein phosphorylation
heart morphogenesis
cardiac ventricle morphogenesis
determination of left/right symmetry
brain development
peripheral nervous system development
endoderm development
mesoderm development
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
embryonic pattern specification
organ morphogenesis
anterior/posterior pattern specification
dorsal/ventral pattern formation
cardioblast differentiation
positive regulation of gene expression
positive regulation of somitomeric trunk muscle development
cerebellum development
midbrain-hindbrain boundary morphogenesis
rhombomere 5 development
rhombomere 6 development
cerebellum formation
locus ceruleus development
cell differentiation
positive regulation of Wnt signaling pathway
neuron differentiation
regulation of cell migration
positive regulation of cell migration
thyroid gland development
midbrain development
hindbrain development
notochord development
otic vesicle formation
midbrain-hindbrain boundary development
embryonic camera-type eye development
embryonic heart tube development
negative regulation of endodermal cell fate specification
otic placode formation
regulation of bone remodeling
determination of dorsal identity
paraxial mesoderm development
neuron fate specification
embryonic neurocranium morphogenesis
skeletal system morphogenesis
oligodendrocyte differentiation
inner ear development
striated muscle cell differentiation
cartilage development
atrial cardiac muscle cell differentiation
ventricular cardiac muscle cell differentiation
pharyngeal system development
retina development in camera-type eye
embryonic retina morphogenesis in camera-type eye
cilium morphogenesis
ectodermal placode formation
somite development
taste bud formation
closure of optic fissure
Kupffer's vesicle development
otic vesicle development
