Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
FGF-8A Recombinant Rabbit Monoclonal Antibody (HL2369)
FIGURE: 1 / 1
FGF-8A Antibody (MA5-50507) in IHC
Immunohistochemical analysis of FGF-8A using FGF-8A Recombinant Monoclonal Antibody (Product # MA5-50507) on 1 day-post-fertilization zebrafish embryo whole mount at a dilution of 1:200 (Green). Tris-HCl buffer, pH 9.0, 20 min at 70°C was used for Antigen retrieval.
Product Details
MA5-50507
Product Specifications
Species Reactivity
Zebrafish
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2369
Immunogen
Recombinant fragment of zebrafish Fgf8a.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3092947
Target Information
FGF-8 is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8a, FGF-8b, FGF-8e and FGF-8f. The human and murine FGF-8a and FGF-8b are identical, unlike human and mouse FGF-8e and FGF-8f, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ace; acerebellar; cb110; etID309886.13; fb73a06; FGF-8; fgf8; Fibroblast growth factor 8; fibroblast growth factor 8 a; ibd5031; secreted protein
Gene Aliases: ace; cb110; etID309886.13; fgf-8; fgf8; fgf8a; id:ibd5031; wu:fb73a06
UniProt ID: (Zebrafish) O57341
Entrez Gene ID: (Zebrafish) 30538
cell fate specification
somitogenesis
positive regulation of protein phosphorylation
heart morphogenesis
cardiac ventricle morphogenesis
determination of left/right symmetry
brain development
peripheral nervous system development
endoderm development
mesoderm development
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
embryonic pattern specification
organ morphogenesis
anterior/posterior pattern specification
dorsal/ventral pattern formation
cardioblast differentiation
positive regulation of gene expression
positive regulation of somitomeric trunk muscle development
cerebellum development
midbrain-hindbrain boundary morphogenesis
rhombomere 5 development
rhombomere 6 development
cerebellum formation
locus ceruleus development
cell differentiation
positive regulation of Wnt signaling pathway
neuron differentiation
regulation of cell migration
positive regulation of cell migration
thyroid gland development
midbrain development
hindbrain development
notochord development
otic vesicle formation
midbrain-hindbrain boundary development
embryonic camera-type eye development
embryonic heart tube development
negative regulation of endodermal cell fate specification
otic placode formation
regulation of bone remodeling
determination of dorsal identity
paraxial mesoderm development
neuron fate specification
embryonic neurocranium morphogenesis
skeletal system morphogenesis
oligodendrocyte differentiation
inner ear development
striated muscle cell differentiation
cartilage development
atrial cardiac muscle cell differentiation
ventricular cardiac muscle cell differentiation
pharyngeal system development
retina development in camera-type eye
embryonic retina morphogenesis in camera-type eye
cilium morphogenesis
ectodermal placode formation
somite development
taste bud formation
closure of optic fissure
Kupffer's vesicle development
otic vesicle development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support