Invitrogen

FGF18 Polyclonal Antibody

查看其他4个FGF18抗体

抗体检测数据 (1)

FGF18 Antibody in Western Blot (WB)

FGF18 Antibody in Western Blot (WB)

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FGF18 Antibody (PA5-106562) in WB

Western blot analysis of FGF18 in NCI-H460 (left lane: treated with blocking peptide). Samples were incubated with FGF18 polyclonal antibody (Product # PA5-106562).

FGF18 Antibody in Western Blot (WB)

Product Image Gallery

FGF18 Antibody in Western Blot (WB) — Western blot analysis of FGF18 in NCI-H460 (left lane: treated with blocking peptide). Samples were incubated with FGF18 polyclonal antibody (Product # PA5-106562).

产品信息

PA5-106562

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

-

免疫组化（石蜡） (IHC (P))

1:50-1:200

-

免疫细胞化学 (ICC/IF)

1:100-1:500

-

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human FGF18(Accession O76093), corresponding to amino acid residues E135-L185.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2854230

产品详细信息

Antibody detects endogenous levels of total FGF18.

靶标信息

FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: FGF; FGF-18; Fibroblast growth factor; Fibroblast growth factor 18; zFGF5

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基因别名: D130055P09Rik; FGF-18; FGF18; UNQ420/PRO856; ZFGF5

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UniProt ID: (Human) O76093, (Mouse) O89101

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Entrez Gene ID: (Human) 8817, (Mouse) 14172

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protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity type 1 fibroblast growth factor receptor binding type 2 fibroblast growth factor receptor binding growth factor activity 1-phosphatidylinositol-3-kinase activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity receptor binding fibroblast growth factor receptor binding growth factor intercellular signal molecule

MAPK cascade angiogenesis regulation of endothelial cell proliferation intramembranous ossification endochondral ossification chondrocyte development signal transduction cell-cell signaling positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway anatomical structure morphogenesis regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine phosphorylation lung development positive regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of chondrocyte differentiation phosphatidylinositol-3-phosphate biosynthetic process positive regulation of MAP kinase activity positive regulation of GTPase activity phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling positive regulation of ERK1 and ERK2 cascade regulation of sprouting angiogenesis positive regulation of endothelial cell chemotaxis to fibroblast growth factor ossification nervous system development cell proliferation