Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-79261
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence in the middle region of human FGF9 (150-164aa SNLYKHVDTGRRYYV).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2746377
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: elbow knee synostosis; FGF; FGF-9; Fibroblast growth factor; Fibroblast growth factor 9; fibroblast growth factor 9 (glia-activating factor); GAF; glia activating factor; Glia-activating factor; HBGF-9; Heparin-binding growth factor 9; M-FGF-9
基因别名: Eks; FGF-9; FGF9; GAF; HBFG-9; HBGF-9; SYNS3
UniProt ID: (Human) P31371, (Rat) P36364, (Mouse) P54130
Entrez Gene ID: (Human) 2254, (Rat) 25444, (Mouse) 14180
protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
fibroblast growth factor receptor binding
growth factor activity
heparin binding
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
receptor binding
growth factor
intercellular signal molecule
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
angiogenesis
osteoblast differentiation
eye development
positive regulation of mesenchymal cell proliferation
chondrocyte differentiation
protein import into nucleus
signal transduction
cell-cell signaling
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
male gonad development
positive regulation of gene expression
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
substantia nigra development
negative regulation of Wnt signaling pathway
male sex determination
embryonic limb morphogenesis
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of activin receptor signaling pathway
phosphatidylinositol-3-phosphate biosynthetic process
inner ear morphogenesis
positive regulation of MAPK cascade
positive regulation of GTPase activity
positive regulation of smoothened signaling pathway
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
regulation of timing of cell differentiation
embryonic digestive tract development
embryonic skeletal system development
positive regulation of epithelial cell proliferation
positive regulation of cell division
positive regulation of cardiac muscle cell proliferation
lung-associated mesenchyme development
positive regulation of canonical Wnt signaling pathway
lung development
cardiac left ventricle morphogenesis
cardiac ventricle development
multicellular organism development
cell differentiation
positive regulation of transcription, DNA-templated
vasculogenesis involved in coronary vascular morphogenesis
