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产品信息
MA5-25144
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI3G7
抗原
Full length human recombinant protein of FHL1 produced in HEK293T cell
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723182
靶标信息
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bA535K18.1; FHL-1; Four and a half LIM domains protein 1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; KYO-T; LIM protein SLIMMER; MGC111107; RP11-535K18.1; Skeletal muscle LIM-protein 1; SLIM
基因别名: FHL-1; FHL1; FHL1A; FHL1B; FLH1A; KYOT; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA
UniProt ID: (Human) Q13642, (Rat) Q9WUH4
Entrez Gene ID: (Human) 2273, (Rat) 25177
regulation of membrane depolarization
muscle organ development
organ morphogenesis
negative regulation of G2/M transition of mitotic cell cycle
cell differentiation
negative regulation of cell growth
positive regulation of potassium ion transport
regulation of potassium ion transmembrane transporter activity
negative regulation of G1/S transition of mitotic cell cycle
multicellular organism development
