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产品信息
PA5-55158
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641623
产品详细信息
Immunogen sequence: QCGDILTNKR FMLDMLYAHN RKSPDDEEKG DGEAGRTQQE AEAVASLATR ISTLQANSQT QDESVRRVDV GCLDNRGSVK AFAEKFNSGD LGRGSISPDA EPNDKVPETA PVQPKTESDY IWDQLM
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 83%.
靶标信息
FHOD3 is a novel member of the formin homology family playing an important role in regulation of the actin cytoskeleton. It contains a DAD (diaphanous auto regulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. FHOD3 is a cytoplasmic protein where the main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. A 1422 amino acid containing formin-related actin-organizing protein, FHOD3 may cause stress fiber formation together with cell elongation and may associate with nestin/NES-based interfilament (IF). Expression of FHOD3 is seen mainly in heart, kidney, and brain.
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生物信息学
蛋白别名: FH1/FH2 domain-containing protein 3; Formactin-2; Formin homolog overexpressed in spleen 2; hFHOS2
基因别名: FHOD3; FHOS2; Formactin2; KIAA1695
UniProt ID: (Human) Q2V2M9
Entrez Gene ID: (Human) 80206
